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Highlights

Methadone

Generic Dolophine, Methadose
METHADONE is a pain reliever. It is used to treat severe pain. The medicine is also used to prevent withdrawal symptoms in people addicted to other drugs. Compare opioids.

Description

Methadone is indicated for the treatment of opioid dependency. A 2009 Cochrane review found that methadone was effective in retaining people in treatment and in the reduction or cessation of heroin use as measured by self-report and urine/hair analysis.

The treatment of opioid-dependent persons with methadone will follow one of two routes.[citation needed] Methadone maintenance therapy (MMT) is prescribed to individuals who wish to abstain from illicit drug use but have failed to maintain abstinence from opioids for significant periods. The duration of methadone maintenance ranges from a few months to lifelong. Methadone reduction programs suit the addicted persons who wish to stop using drugs completely. The length of the reduction program will depend on the starting dose and speed of reduction, this varies between clinics and from person to person. However, methadone abuse does carry the potential for dependence. When used correctly, methadone maintenance has been found to be medically safe and non-sedating, and provides a slow recovery from opioid addiction. It is also indicated for pregnant women addicted to opioids.

Adverse effects of methadone:

  • Sedation
  • Diarrhea or constipation
  • Flushing
  • Perspiration and sweating
  • Heat intolerance
  • Dizziness or fainting
  • Weakness
  • Chronic fatigue, sleepiness and exhaustion
  • Sleep problems such as drowsiness, trouble falling
  • asleep (Insomnia), and trouble staying asleep
  • Constricted pupils
  • Dry mouth
  • Nausea and vomiting
  • Low blood pressure
  • Difficulty urinating
  • Mood changes, euphoria, disorientation

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